What form factor and interface does the HPE P73300-B21 use?

2.5-inch Small Form Factor (SFF) with U.3 (SFF-8639) connector supporting NVMe over PCIe. Tri-mode compatibility ensures flexibility across NVMe/SAS/SATA backplanes in HPE servers.

What workloads is this SSD optimized for?

Read-intensive workloads >70% reads like analytics, virtualization, big data lakes, VDI, and web serving. Uses 3D TLC NAND for high capacity at lower cost than write-intensive drives.

Is the P73300-B21 hot-pluggable?

Yes, fully hot-plug capable for non-disruptive drive replacement and scalability in enterprise servers, minimizing downtime during maintenance or capacity upgrades.

What servers is this SSD compatible with?

Designed for HPE ProLiant, Apollo, and Synergy platforms. Provides guaranteed performance, management, and lifecycle support when deployed in qualified HPE environments.

How does NVMe benefit performance vs SAS/SATA?

NVMe reduces latency to microseconds via direct PCIe access, supports massive parallel IOPS, and delivers GB/s sequential throughput - 3-10x improvement over legacy protocols for read-heavy workloads.

What NAND technology powers this drive?

3D Triple-Level Cell (TLC) NAND flash with vertically stacked layers for higher density/reliability vs 2D NAND, optimized for read endurance in enterprise applications.

P73300-B21 - HPE P73300-B21 15.36TB NVMe U.3 Read Intensive SFF SSD

Name: HPE P73300-B21 15.36TB NVMe U.3 Read Intensive SFF SSD
Brand: HPE
SKU: P73300-B21

P73300-B21 - HPE P73300-B21 15.36TB NVMe U.3 Read Intensive SFF SSD | US IT Hardware

Product overview

The HPE P73300-B21 is a 15.36TB NVMe read-intensive solid state drive designed for enterprise environments requiring high-capacity storage with optimized read performance. Featuring a 2.5-inch Small Form Factor (SFF) with U.3 interface, it supports hot-plug operation for seamless maintenance in HPE ProLiant, Apollo, and Synergy servers. Built on 3D TLC NAND flash, this SSD excels in workloads exceeding 70% reads, such as data analytics, cloud computing, virtualization, and big data processing. The NVMe protocol over PCIe delivers ultra-low latency in microseconds, high sequential throughput in GB/s, and massive random read IOPS, outperforming legacy SAS/SATA drives. U.3 connector ensures compatibility across NVMe, SAS, and SATA environments. As an enterprise-class solution, it provides high density to reduce rack space, power, and cooling costs while maintaining reliability for 24/7 operations. Ideal for in-memory databases, VDI, web serving, and data lakes where cost-per-TB efficiency is critical without needing write-intensive endurance.

15.36TB Read Intensive NVMe SSD.
SFF 2.5in U.3 PCIe NVMe interface.
3D TLC NAND for analytics/VDI.
Hot-plug enterprise compatibility.
HPE ProLiant/Apollo/Synergy support.
>70% read workload optimized.

Expedited and overnight shipping options are available at checkout, priced by destination and service.
Purchase orders accepted from qualified institutions.
Refunds within 14 days and replacements within 30 days of delivery with an RMA (25% restocking fee on customer-initiated returns), and every part carries our Standard 30-Day Warranty - see our return policy or contact US IT Hardware.

Featuring

Manufacturer part #	P73300-B21
Brand	HPE
Condition	New
Model	P73300-B21
Protocol	NVMe 1.4; Tri-mode U.3 (NVMe/SAS/SATA compatible)
Use Cases	Analytics, virtualization, big data, cloud, VDI, web serving
Device Type	Internal SSD - Enterprise
Product Line	HPE NVMe SSDs
Product Type	NVMe Solid State Drive - Read Intensive
Compatibility	HPE ProLiant, Apollo, Synergy servers
Hot Pluggable	Yes

Compatible systems

Native support in HPE ProLiant Gen10+, Apollo, Synergy with major hypervisors and Linux/Windows Server.

HPE ProLiant
Model: DL380
Form factor: 2U Rack
Generation: Gen10 Plus
Qualified for NVMe U.3 bays
HPE Apollo
Model: 2000 Gen10
Form factor: 2U Rack
Generation: Gen10
High-density storage support
HPE Synergy
Model: 480 Gen10
Form factor: Blade
Generation: Gen10
Composable infrastructure compatible

Best for

Data Analytics
Optimized for >70% read workloads in Hadoop, Spark clusters processing large datasets with high random read IOPS and low latency.
Virtualization
VMware vSphere, Hyper-V hosts with multiple VMs accessing scattered data blocks simultaneously for consistent performance.
Big Data Lakes
Object storage and data lake environments serving high-volume read requests from analytics tools like Tableau, Power BI.

Details

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NVMe Enterprise & Data Center SSDs 15.36TB Enterprise SSDs HPE Enterprise SSDs 2.5-inch Enterprise SSDs

Connector	U.3 12-lane (PCIe x4)
Interface	U.3 (SFF-8639) - NVMe over PCIe

HPE P73300-B21 15.36TB NVMe U.3 Read Intensive SFF SSD

Product overview

Featuring

Compatible systems

Best for

Details

Shipping, warranty & returns

Customer reviews

Storage

Physical Characteristics

Interface/Ports

Frequently asked questions

HPE P73300-B21 15.36TB NVMe U.3 Read Intensive SFF SSD

Product overview

Featuring

Compatible systems

Best for

Details

Shipping, warranty & returns

Customer reviews

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Storage

Physical Characteristics

Interface/Ports

Frequently asked questions