What interface does the HPE P49273-B21 use?

The drive uses SAS 24Gbps (SAS-4) dual-port interface, backward compatible with 12Gbps SAS controllers. This provides up to 2400 MB/s theoretical bandwidth per port, ideal for high-availability RAID configurations in HPE ProLiant servers.

Is this SSD hot-swappable?

Yes, bundled with HPE SmartDrive Carrier tray for hot-swap operation in supported ProLiant bays. Features LED status indicators and iLO integration for safe drive extraction without server reboot.

What workloads is it optimized for?

Read Intensive workloads with >70% read operations, such as web servers, virtualization datastores, and database read replicas. Rated ~1 DWPD endurance suitable for low-write enterprise applications.

Which HPE servers support this drive?

Compatible with ProLiant Gen10 and Gen11 DL/ML models featuring SAS 24G backplanes or controllers like MR408i-o/MR416i-a. Verify HPE SSD selector tool for specific firmware/BIOS requirements.

What form factor does it use?

2.5-inch SFF (15mm height) with standard HPE tray, fitting all SFF drive cages in rackmount and tower ProLiant servers for high-density storage.

Does it support encryption?

Supports TCG Opal 2.0 self-encrypting drive (SED) capabilities via HPE firmware, enabling hardware-based AES-256 encryption managed through server controllers.

P49273-B21 - HPE P49273-B21 3.84TB SAS 24Gbps RI SFF SSD

Name: HPE P49273-B21 3.84TB SAS 24Gbps RI SFF SSD
Brand: HPE
SKU: P49273-B21
Price: 2132 USD
Availability: InStock

P49273-B21 - HPE P49273-B21 3.84TB SAS 24Gbps RI SFF SSD | US IT Hardware

Product overview

The HPE P49273-B21 is a 3.84TB SAS 24Gbps Small Form Factor (SFF) Read Intensive Solid State Drive based on the Samsung PM1653 controller, bundled with HPE SmartDrive Carrier for seamless integration into ProLiant Gen10 and Gen11 servers. This enterprise-class SSD provides high-performance sequential and random read operations ideal for read-heavy workloads such as web servers, boot volumes, and caching layers. With SAS 24Gbps interface, it supports triple the bandwidth of previous 12Gbps SAS drives, enabling faster data transfers in RAID configurations and direct-attached storage. The read intensive endurance rating suits applications with low write workloads, offering optimized cost-per-TB for capacity-focused deployments. Hot-swap capability ensures minimal downtime during maintenance, while HPE firmware enhancements provide compatibility with iLO management, power profiling, and predictive failure analysis. Designed for 24/7 enterprise operation, it features power-loss protection and thermal throttling for reliability in dense rack environments. Compatible with HPE ProLiant DL/ML servers supporting SAS 24G backplanes, this SSD enhances virtualization hosts, database read replicas, and content delivery systems by delivering consistent low-latency I/O under sustained loads.

3.84TB SAS 24Gbps RI SFF SSD.
PM1653 controller TLC NAND.
HPE SmartDrive hot-swap tray.
Read Intensive 1 DWPD endurance.
ProLiant Gen10/11 compatible.
Dual-port SAS-4 24Gbps interface.

Expedited and overnight shipping options are available at checkout, priced by destination and service.
Purchase orders accepted from qualified institutions.
Refunds within 14 days and replacements within 30 days of delivery with an RMA (25% restocking fee on customer-initiated returns), and every part carries our Standard 30-Day Warranty - see our return policy or contact US IT Hardware.

Featuring

Product Type
Manufacturer part #	P49273-B21
Brand	HPE
Condition	Refurbished
MTBF	2M hours typical
Model	PM1653
Endurance	RI 1 DWPD typical for capacity
NAND Type	TLC
Flash Type	3D TLC NAND
Device Type	Solid State Drive - Hot-Swap
Carrier Type	HPE SmartDrive Carrier with Tray
Product Line	PM1653

Compatible systems

Optimized for HPE ProLiant Gen10/11 servers with SAS 24G support. Full OS compatibility via standard drivers.

HPE ProLiant
Model: DL380
Form factor: 2U Rack
Generation: Gen10
SAS 24G controller required
HPE ProLiant
Model: DL360
Form factor: 1U Rack
Generation: Gen11
iLO 6 firmware supported
HPE ProLiant
Model: ML350
Form factor: Tower
Generation: Gen10
SFF bays with SAS backplane

Best for

Web Servers
High-read OLTP and static content serving with Apache/Nginx on ProLiant DL380, leveraging fast sequential reads for low-latency page delivery.
Virtualization Hosts
VMware vSphere/ESXi hypervisors on Gen10/11 servers requiring boot/OS volumes with read-intensive access patterns across multiple VMs.
Caching Layers
Redis/Memcached in-memory caches or Varnish reverse proxies benefiting from high random read IOPS in enterprise data centers.

Height	15mm SFF
Form Factor	2.5in SFF

Ports	Single Port SAS
Interface	SAS 24Gbps

HPE P49273-B21 3.84TB SAS 24Gbps RI SFF SSD

Product overview

Featuring

Compatible systems

Best for

Details

Shipping, warranty & returns

Customer reviews

Storage

Network & Communication

Security

Power Consumption

Physical Characteristics

Environmental

Interface/Ports

Frequently asked questions

HPE P49273-B21 3.84TB SAS 24Gbps RI SFF SSD

Product overview

Featuring

Compatible systems

Best for

Details

Shipping, warranty & returns

Customer reviews

Shop these collections

Storage

Network & Communication

Security

Power Consumption

Physical Characteristics

Environmental

Interface/Ports

Frequently asked questions